Inclusion criteria (let op korte versie, zie full protocol voor details)

• ECOG/WHO performance 0-1
• Pathologically proven NSCLC, staged according to the 8th edition of the AJCC Staging Manual, with a clinical indication for concurrent CRT
• Pathology proven N2 or N3 lymph node metastasis
• The patient is able to receive concurrent CRT. (0=no, 1=yes)
• The patient is operable to the discretion of the treating pulmonary physician, surgeon and anesthesiologist, based on lung function testing and performance scoring.

Exclusion criteria

• Irresectable primary lung tumor before start of concurrent CRT.
• Pneumonectomy deemed necessary (by the treating surgeon) to achieve a complete resection (R0).
• Sulcus superior tumor with invasion of the thoracic wall.
• cT3-4 based on satellite nodus/lesion in the ipsilateral lung.
• Patients with a locoregional recurrence or a second primary lung cancer.
• Patients with prior treatment with radiotherapy on the lung.
• Patients with a history of other malignancies (for exceptions see full protocol)
• Small cell lung cancer or a pulmonary carcinoid tumor.