Studieoverzicht

Study name: PRT3789-01

Histology NSCLC
Tumor stage Stage IV
Host / recruiting sites LUMC
Enrollment Recruiting
Therapy line Later line (≥2L)
Design

Open-label, multi-center, first-in-human fase 1 dosis escalatie studie

Intervention

PRT3789

Key outcome parameters

Safety en tolerability

Key inclusion criteria

Advanced of gemetastaseerde solide maligniteit met SMARCA4 mutatie (NGS) of verlies van SMARCA4 (IHC)

Progressie op standard of care systeemtherapie

Key exclusion criteria

Symptomatische CNS metastasen

Contact information